Jared Goff passed for 315 yards and three touchdowns but Detroit lost top defensive player Aidan Hutchinson in a 47-9 thumping of Dallas in Arlington, Texas on Sunday.
Hutchinson suffered a serious left leg injury in the third quarter while sacking Dallas quarterback Dak Prescott and was carted off the field. After the game, Lions coach Dan Campbell said it was a tibia injury and that Hutchinson would remain in the Dallas area while the team flew back to Detroit.
David Montgomery rushed for 80 yards and two touchdowns for the Lions (4-1), who have won three in a row.
Prescott passed for 178 yards and was intercepted twice, both by Brian Branch, as the Cowboys (3-3) dropped to 0-3 in home games. Cooper Rush relieved Prescott and was 8-for-11 passing for 46 yards and an interception. CeeDee Lamb had seven catches for 89 yards for Dallas.
Bears 35, Jaguars 16
Rookie Caleb Williams tossed a career-best four touchdown passes to lead Chicago over Jacksonville at Tottenham Hotspur Stadium in London. His four scoring tosses helped the Bears (4-2) win their third game in a row.
Williams continued to impress, completing 23 of 29 passes for 226 yards and an interception. He also ran for 56 yards on four attempts. It was Williams’ third multi-touchdown performance in his past four starts. He finished with a 124.4 passer rating.
Jacksonville (1-5) failed to put together back-to-back wins after snapping a four-game losing streak last week. Trevor Lawrence completed 23 of 35 passes for 234 yards and threw two touchdown passes and an interception. The pick led to a 1-yard touchdown by D’Andre Swift early in the fourth quarter to give the Bears their final points of the game.
Colts 20, Titans 17
Joe Flacco threw two touchdown passes, including the game-winner in the fourth quarter as Indianapolis rallied for a win over Tennessee in Nashville, Tenn.
Flacco, who was 22 of 38 for 189 yards and an interception, found Michael Pittman Jr. for a 5-yard strike on third-and-9 with 7:27 left as Indianapolis improved to 3-3. John Downs had seven catches for 66 yards and a score for the Colts, who won despite star running back Jonathan Taylor (ankle) missing his second straight game.
In his first start since Sept. 30, Tennessee quarterback Will Levis hit 16 of 27 passes for only 95 yards with a touchdown and a fourth-quarter interception. Tony Pollard rushed for a game-high 93 yards and a touchdown for the Titans (1-4), who are 0-3 at home.
Eagles 20, Browns 16
A.J. Brown and DeVonta Smith each caught a touchdown pass in their return to action as Philadelphia held off visiting Cleveland, handing the Browns their fourth straight loss.
Smith missed the previous game with a concussion, while Brown sat out the last three contests with a hamstring injury. In this one, they combined for nine catches for 180 yards from Jalen Hurts (16-of-25 passing, 264 yards, two TDs, no turnovers) as the Eagles (3-2) survived down the stretch.
Smith broke a 13-13 tie with 7:54 remaining when he caught a shallow cross and ran unobstructed down the right sideline for a 45-yard touchdown. Cleveland (1-5) settled for Dustin Hopkins’ 31-yard field goal with 3:54 left.
Texans 41, Patriots 21
C.J. Stroud threw for three touchdowns to lift Houston to a win over New England in Foxborough, Mass.
Stroud completed 20 of 31 passes for 192 yards and was picked off once as Houston (5-1) spoiled Drake Maye’s first career start. Maye, selected third overall by New England in this year’s draft, finished with 243 yards, three scores and two picks on 20-of-33 passing. His 40-yard strike to Kayshon Boutte before the first half was his first NFL TD pass.
Joe Mixon returned from a three-game absence to rack up 132 yards from scrimmage (102 rushing, 30 receiving) for the Texans. He rushed for a touchdown and caught another. Stefon Diggs was one of Stroud’s favorite targets, hauling in six catches for 77 yards and a score.
After seeing its first five drives end in four punts and a pick, New England (1-5) came to life just before the break, pulling within 14-7 on Maye’s 40-yard scoring strike to Kayshon Boutte with 11 seconds left in the first half.
Packers 34, Cardinals 13
Jordan Love matched his career best of four touchdown passes to lead Green Bay to an easy victory over visiting Arizona.
Love completed 22 of 32 passes for 258 yards with one interception to help the Packers (4-2) win their second straight game. Love has thrown 10 touchdown passes in three games since returning from a knee injury. Green Bay’s Romeo Doubs caught two touchdown passes one week after serving a suspension for conduct detrimental to the team.
Kyler Murray also was 22-of-32 passing while accumulating 214 yards and one touchdown for the Cardinals (2-4), who lost for the third time in four games. Michael Wilson caught a touchdown pass while Trey McBride had eight receptions for 96 yards. Arizona’s Marvin Harrison Jr. sustained a first-half concussion and missed the rest of the game.
Buccaneers 51, Saints 27
Baker Mayfield passed for 325 yards and four touchdowns and visiting Tampa Bay defeated New Orleans. Mayfield overcame three interceptions to complete a tumultuous week in which the Bucs (4-2) relocated to New Orleans on Tuesday to avoid Hurricane Milton.
Sean Tucker racked up 192 yards from scrimmage (136 rushing, 56 receiving) with two touchdowns, and Chris Godwin had 11 catches for 125 yards and two touchdowns as Tampa Bay squandered a 17-0 first-quarter lead before outscoring the Saints 27-0 in the second half and finishing with 594 yards.
Ravens 30, Commanders 23
Lamar Jackson threw for 323 yards and a touchdown as Baltimore (4-2) earned a victory over Washington and rookie quarterback Jayden Daniels. Jackson was 20-of-26 passing with an interception and added 40 yards rushing on 11 carries, while improving to 22-3 against NFC teams.
Ravens running back Derrick Henry had 132 yards on 24 carries with two touchdowns while becoming the first player to rush for a touchdown in each of his first six games since LaDainian Tomlinson in 2005.
Daniels was 24-of-35 passing for 269 yards and two touchdowns, while also leading the Commanders (4-2) with 22 rushing yards on six attempts.
Steelers 32, Raiders 13
Justin Fields passed for 145 yards and rushed for 59 yards and two touchdowns, and Pittsburgh pulled away for a win over host Las Vegas.
Najee Harris had 14 carries for 106 yards and a touchdown for Pittsburgh (4-2), which snapped a two-game skid. Chris Boswell added four field goals. Russell Wilson was active for the first time this season but served as the backup to Fields.
Aidan O’Connell completed 27 of 40 passes for 227 yards, one touchdown and one interception in his first start of the season for Las Vegas (2-4). Alexander Mattison had a rushing touchdown and Kristian Wilkerson had a touchdown catch.
Chargers 23, Broncos 16
Justin Herbert passed for 237 yards and a touchdown and Cameron Dicker kicked three field goals as visiting Los Angeles defeated Denver.
Los Angeles (3-2) scored the first 23 points before holding on to stop the Broncos’ three-game winning streak. Denver fell to 3-3. Quarterback Bo Nix was 19-for-33 passing for 216 yards with two touchdowns and an interception.
Chargers coach Jim Harbaugh briefly exited the game in the first quarter with an illness, which Harbaugh revealed in his postgame press conference was arrhythmia. Harbaugh was examined in the team’s medical tent on the sideline before being taken to the locker room for further evaluation. He returned to the sideline soon after.
Falcons 38, Panthers 20
Bijan Robinson ran for two touchdowns, Tyler Allgeier gained 105 yards on the ground and Atlanta fended off Carolina to win in Charlotte, N.C.
Kirk Cousins threw for 225 yards and a touchdown without an interception as the Falcons (4-2) won their third game in a row — all against NFC South rivals. Allgeier, who posted a touchdown and a two-point conversion run, had 18 carries and Robinson picked up 95 rushing yards on 15 attempts.