USC’s Moss throws Holiday Bowl-record 6 TD passes in 42-28 win against No. 16 Louisville

Southern California wide receiver Tahj Washington (16) celebrates a touchdown with tight end Kade Eldridge (88) during the first half of the Holiday Bowl NCAA college football game against Louisville Wednesday, in San Diego. (AP Photo/Denis Poroy)

Louisville wide receiver Kevin Coleman (3) is tackled by Southern California safety Bryson Shaw (27) and linebacker Mason Cobb (13) during the first half of the Holiday Bowl NCAA college football game Wednesday, in San Diego. (AP Photo/Denis Poroy)

Southern California wide receiver Makai Lemon (24) makes a catch in front of Louisville linebacker Antonio Watts (35) during the first half of the Holiday Bowl NCAA college football game Wednesday, in San Diego. (AP Photo/Denis Poroy)

SAN DIEGO — With Caleb Williams watching from the sideline, Miller Moss threw a Holiday Bowl-record six touchdown passes in his first college start and Southern California ended a frustrating season by beating No. 16 Louisville 42-28 Wednesday night.