A Canadian study that many experts say has major flaws has revived debate about the value of mammograms. The research suggests that these screening X-rays do not lower the risk of dying of breast cancer while finding many tumors that do not need treatment.
The study gives longer follow-up on nearly 90,000 women who had annual breast exams by a nurse to check for lumps plus a mammogram, or the nurse’s breast exam alone. After more than two decades, breast cancer death rates were similar in the two groups, suggesting little benefit from mammograms.
It’s important to note that this study did not compare mammograms to no screening at all, as most other research on this topic has. Many groups have not endorsed breast exams for screening because of limited evidence that they save lives.
Critics of the Canadian study also say it used outdated equipment and poor methods that made mammograms look unfairly ineffective.
The study was published Wednesday in the British journal BMJ.
Breast cancer is the leading type of cancer and cause of cancer deaths in women worldwide. Nearly 1.4 million new cases are diagnosed each year. Many studies have found that mammography saves lives, but how many and for what age groups is debatable. It also causes many false alarms and overtreatment of cancers never destined to become life-threatening.
In the U.S., a government-appointed task force that gives screening advice does not back mammograms until age 50, and then only every other year. The American Cancer Society recommends them every year starting at age 40. Other countries screen less aggressively. In Britain, for example, mammograms are usually offered only every three years.
The Canadian study has long been the most pessimistic on the value of mammograms. It initially reported that after five years of screening, 666 cancers were found among women given mammograms plus breast exams versus 524 cancers among those given the exams alone.
After 25 years of follow-up, about 500 in each group died, suggesting mammograms were not saving lives. The similarity in the death rates suggests that the 142 “extra” cancers caught by mammograms represent overdiagnosis — tumors not destined to prove fatal, study leaders concluded.